Abstract
We present a 58 years old woman with multiple sclerosis diagnosed in 2007, she was treated with interferon and methylprednisolone with a stable disease until last year. Recently she had had multiple episodes of exacerbations.
Patient was admitted for a rapidly progressive neurological deterioration. When evaluated the patient had a Glasgow scale of 4/15 (Best eye response: 2, Best verbal response: 1, Best motor response: 1). Case was evaluated in a medical board, and was considered an atypical Marburg variant of multiple sclerosis. She was treated with immunoglobulin and mitoxantrone without clinical improvement. Later she developed a distributive shock leading to death.
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