Abstract
Introduction: Deep brain stimulation (DBS) is effective in treating Parkinson's Disease (PD) through the use of an implantable pulse generator (IPG), which can be rechargeable (r-IPG) or non-rechargeable (nr-IPG). This study examines evidence on these devices regarding their duration, quality of life, adverse events, and costs in patients with PD.
Materials and methods: Rapid Systematic Review following Cochrane Group guidelines.
Results: Of 10 studies, 2 included only PD patients, and the others included various neurological disorders. Patients using an r-IPG from the start of treatment or as a replacement reported high satisfaction, with no significant differences compared to nr-GPI. In PD patients, the average replacement time for nr-GPI was 5.1 years, while r-GPI had a lifespan of 9 to 15 years. Although r-GPI reduces surgical interventions, it presents specific risks, such as recharging failures and missed charging sessions, while nr-GPI requires frequent replacements and is associated with a higher infection risk. The use of r-GPI showed significant long-term cost savings.
Discussion: Studies indicate that r-GPI offers benefits in satisfaction, lower complication risk, and greater long-term cost-effectiveness due to the reduced need for replacements. The specific risks of each device suggest the importance of personalized selection based on the patient’s needs and preferences.
Conclusions: nr-GPI devices have a shorter duration, while r-GPI devices have demonstrated greater long-term cost-effectiveness and higher patient satisfaction rates.
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